Drs. Mrksich and Jewett have developed a new method for engineering metabolic pathways that combine cell-free protein synthesis and self-assembled monolayer desorption ionization (SAMDI) mass spectrometry. Their paper “High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA” was recently published in
Science Advances. 

Science Advances article

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