The Center for Synthetic Biology hosted fifth graders from the Western Springs School District. The fifth graders learned about current research efforts in the Center from faculty and students. They also had the opportunity for hands on experiments.
Discovery of gene regulatory networks (GRNs) is crucial for gaining insights into biological processes involved in development or disease. Investigating the temporal dynamics of regulatory networks is particularly insightful. We introduce Sliding Window Inference for Network Generation (SWING), which uniquely accounts for temporal information underlying GRNs, such as protein synthesis and posttranslational modifications. We validate SWING in both in silico and in vitro experimental systems, highlighting improved performance in identifying time-delayed edges and illuminating network structure. SWING performance is robust to user-defined parameters, enabling identification of regulatory mechanisms from time-series gene expression data.
We are looking for eight highly motivated students with an interest in research at the interface of engineering, biology, mathematics, and chemistry to participate in the 2018 summer research program … Continued
Sarah Stainbrook (Tyo Lab), Anne dAquino (Jewett Lab), Michael Jewett, Weston Kightlinger (Jewett Lab), Cameron Glasscock (Lucks Lab), and Patrick  Donahue (Leonard Lab) represented the Center at the Synthetic Biology: Engineering, Evolution, … Continued
Center’s for Synthetic Biology Faculty member,  Dr.  Julius B Lucks, was quoted in The Wall Street Journal about new CRISPR diagnostics technology SHERLOCK . Full Article can  be found at the … Continued
