Joint Publications
- Jaroentomeechai T, Stark JC, Natarajan A, Glasscock C, Yates L, Hsu KJ, Mrksich M, Jewett MC, DeLisa MP (2018) “Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery” Nature Communications 9: 2686
- Kightlinger W, Lin L, Rosztoczy M, DeLisa MP, Mrksich M, Jewett MC (2018) “Design of glycosylation sites by rapid synthesis and analysis of glycosyltransferase” Nature Chemical Biology 14: 627-635
- Younger AKD, Su PY, Shepard AJ, Udani SV, Cybulski TR, Tyo KE, Leonard JN (2018) “Development of novel metabolite-responsive transcription factors via transposon-mediated protein fusion” Protein Engineering, Design, and Selection 31(2): 55-63
- Hartfield RM, Schwarz KA, Muldoon JJ, Bagheri N, Leonard JN (2017) “Multiplexing engineered receptors for multiparametric evaluation of environmental ligands” ACS Synthetic Biology 6: 2042-2055
- Xu A, Szymczak L, Mrksich M, Bagheri N (2017) “Machine learning on SAMDI Mass spectrometry signal to noise ratio improves peptide array designs” Analytical Chemistry 89: 9039-9047
- Kelleher NL, Jewett MC, Mrksich M, et al (2018) “How many human proteoforms are there?” Nature Chemical Biology 14: 206-214
- Glasscock CJ, Lazar JT, Biggs BW, Arnold JH, Kang MK, Tullman-Ercek D, Tyo K, Lucks JB (2019) “Dynamic control of pathway expression with riboregulated switchable feedback promoters” bioRxiv 529180; doi: 10.1101/529180
- Meyer AJ, Saaem I, Silverman AD, Varaljay V, Mickol R, Blum SM, Tobias AV, Schwalm ND, Mojadedi W, Onderko E, Bristol C, Liu S, Casini A, Eluere R, Moser F, Drake C, Gupta M, Kelley-Lougnane N, Lucks JB, Akingbade KL, Lux MW, Glaven SM, Crookes-Goodson WJ, Jewett MC, Gordon B, Voigt CA (2019) “Organism engineering for the bioproduction of the triaminotrinitrobenzene (TATB) precursor phloroglucinola (PG)” ACS Synthetic Biology doi:10.1021/acssynbio.9b00393
- Yesselman JD, Eiler D, Carlson ED, Gotrik MR, d’Aquino AE, Ooms AN, Kladawang W, Carlson PD, Shi X, Constantino DA, Hershlag D, Lucks JB, Jewett MC, Kieft JS, Das R (2019) “Computational design of three-dimensional RNA structure and function” Nature Nanotechnology doi:10.1038/s41565-019-0517-8
- Xue AY, Yu AM, Lucks JB, Bagheri N (2019). “DUETT quantitatively identifies novel events in nascent RNA structural dynamics from chemical probing data” Bioinformatics doi:10.1093/bioinformatics/btz449
- Silverman AD, Kelley-Loughnane N, Lucks JB, Jewett MC (2019) “Deconstructing cell-free extract preparation for in vitro application of transcriptional genetic circuitry” ACS Synthetic Biology 8: 403-414; doi: 10.1021/acssynbio.8b00430.
- Thavarajah W, Silverman AD, Verosloff M, Kelley-Loughnane N, Jewett MC, Lucks JB (2019) “Point-of-use detection of environmental fluoride via a cell-free riboswitch-based biosensor” bioRxiv: 10.1101/712844 (In Revision ACS Synthetic Biology)
- Liu X, Silverman AD, Alam KK, Iverson E, Lucks JB, Jewett MC, Raman S (2019) “Design of a transcriptional biosensor for the portable, on-demand detection of cyanic acid” bioRxiv: 10.1101/736355 (In Revision ACS Synthetic Biology)
- Silverman AD, Akova U, Alam KK, Jewett MC, Lucks JB (2019) “Design and optimization of a cell-free atrazine biosensor” bioRxiv: 10.1101/779827 (In Revision ACS Synthetic Biology)
- Kightlinger W, Duncker K, Ramesh A, Thames A, Natarajan A, Stark JC, Yang A, Lin L, Mrksich M, DeLisa MP, Jewett MC (2019) “A cell-free biosynthesis platform for modular construction of protein glycosylation pathways” Nature Communications 10: 5404
- O’Kane PT, Dudley QM, McMillan AK, Jewett MC, Mrksich M (2019) “High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA” Science Advances 5(6): EAAW9180
- Donahue PS, Draut JW, Muldoon JJ, Edelstein HI, Bagheri N, Leonard JN (2019) “COMET: A toolkit for composing customizable genetic programs in mammalian cells” bioRxiv: 769794; doi: 10.1101/769794
- Muldoon JJ, Chuang Y, Baheri N, Leonard JN (2019) “Macrophages employ quorum licensing to regulate collective activation” bioRxiv 610592; doi: 10.1101/610592
- Stainbrook SC, Yu JS, Reddick MP, Bagheri N, Tyo KEJ (2017) “Modulating and evaluating receptor promiscuity through directed evolution and modeling” Protein Engineering, Design and Selection 30(6): 455-465; doi: 10.1093/protein/gzx018
- Thavarajah W, Verosloff MS, Jung JK, Alam KK, Miller JD, Jewett MC, Young SL, Lucks JB (202) "A primer on emerging field-deployable synthetic biology tools for democratizing global water quality monitoring" NPJ Clean Water 3:18
- Kennedy NW, Hershewe JM, Nichols TM, Roth EW, Wilke CD, Jewett MC, Tullman-Ercek D (2020) "Apparent size and morphology of bacterial microcompartments varies with technique" PLOS ONE; doi: 10.1371/journal.pone.0226395
- Techner JM, Kightlinger W, Lin L, Hershewe J, Ramesh A, DeLisa MP, Jewett MC, Mrksich M (2020) "High-throughput synthesis and analysis of intact glycoproteins using SAMDI-MS" Analytical Chemistry 92(2): 1963-1971
- Lin L, Kightlinger W, Hockenberry AJ, Jewett MC, Mrksich M (2020) "Sequential glycosylation of protein via substrate specific N-glycosyltransferases" ACS Central Science 6: 144-154
- Silverman AD, Karim AS, Jewett MC (2020) "Cell-Free Gene Expression: An Expanded Repertoire of Applications" Nature Reviews Genetics 21, 151-170
- Jung JK, Alam KK, Verosloff MS, et al. (2020) "Cell-free biosensors for rapid detection of water contaminants" Nat. Biotechnol. 38, 1451–1459; doi: 10.1038/s41587-020-0571-7
- Kafader JO, Melani RD, Durbin KR et al. (2020) "Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes" Nat Methods 17, 391–394; doi: 10.1038/s41592-020-0764-5
- Pluchinsky AJ, Wackelin DJ, Huang X, Arnold FH, Mrksich M (2020) "High Throughput Screening with SAMDI Mass Spectrometry for Directed Evolution" Journal of the American Chemical Society 142 (47), 19804-19808 DOI: 10.1021/jacs.0c07828
- Hershewe JM, Warfel KF, Iyera SM, Peruzzi JA, Sullivand CJ, Rothe EW, DeLisaf MP, Kamat NP, Jewett MC (2021) "Improving cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles" Nature Communications 12, 2363
- Liu Y, Davis RG, Thomas PM, Kelleher NL, Jewett MC (2021) "In vitro-Constructed Ribosomes Enable Multi-site Incorporation of Noncanonical Amino Acids into Proteins" Biochemistry 60 (3), 161-169; doi: 10.1021/acs.biochem.0c00829
- Muldoon JJ, Kandula V, Hong M, Donahue PS, Boucher JD, Bagheri N, Leonard JN (2021) "Model-guided design of mammalian genetic programs" Science Advances eabe9375
- Fackler N, Heijstra BD, Rasor BJ, Brown H, Martin J, Ni Z, Shebek KM, Rosin RR, Simpson SD, Tyo KE, Giannone RJ, Hettich RL, Tschaplinski TJ, Leang C, Brown SD, Jewett MC, Köpke M (2021) "Stepping on the Gas to a Circular Economy: Accelerating Development of Carbon-Negative Chemical Production from Gas Fermentation" Annu Rev Chem Biomol Eng. doi: 10.1146/annurev-chembioeng-120120-021122.
- Verosloff MS, Corcoran WK, Dolberg TB, Bushhouse DZ, Leonard JN, Lucks JB (2021) "RNA Sequence and Structure Determinants of Pol III Transcriptional Termination in Human Cells" Journal of Molecular Biology doi: /10.1016/j.jmb.2021.166978.